Why get vaccinated?

    Japanese encephalitis (JE) is a serious infection caused by the Japanese encephalitis virus.

    •     It occurs mainly in rural parts of Asia

    •     It is spread through the bite of an infected mosquito. It does not spread from person to person

    •     Risk is very low for most travelers. It is higher for people living in areaswhere the disease is common, or for people traveling there for long periods of time

    •     Most people infected with JE virus don't have any symptoms. Others might have symptoms as mild as a fever and headache, or as serious as encephalitis (brain infection)

    •     A person with encephalitis can experience fever, neck stiffness, seizures, and coma. About 1 person in4 with encephalitis dies. Up to half of those who don't die have permanent disability

    •     It is believed that infection in a pregnant woman could harm her unborn baby

    JE vaccine can help protect travelers from JE disease.

    JE vaccine

    Japanese encephalitis vaccine is approved for people 8 months of age and older. It is recommended for travelers to Asia who:

    •     Plan to spend at least a month in areas where JE occurs

    •     Plan to travel for less than a month, but will visit rural areas and spend a lot of time outdoors

    •     Travel to areas where there is a JE outbreak

    •     Are not sure of their travel plans

    The vaccine is given as 4-dose series. Primary immunization consists 2 doses, with interval of 7 days. Booster dose (3rd dose) at 1 month to 1 year after 2nd dose. Depending on risk of exposure, another booster dose at 3 to 4 years later. The second dose should be given at least a week before travel. 

    The best way to prevent JE is to avoid mosquito bites. 


    Some people should not get this vaccine

    Anyone who has had a severe (life-threatening) allergic reaction to a dose of JE vaccine should not get another dose.Anyone who has a severe (life threatening) allergy to any component of JE vaccine should not get the vaccine. 

    Tell your doctor if you have any severe allergies that you know of.

    Pregnant women should usually not get JE vaccine. If you are pregnant, check with your doctor. If you will be traveling for fewer than 30 days, especially if you will be staying in urban areas, tell your doctor. You might not need the vaccine.

    Risks of a vaccine reaction

    With a vaccine, like any medicine, there is a chance of side effects. When side effects happen, they are usually mild and go away on their own.

    After vaccination, please stay in clinic observation area for 30 minutes.

    Mild problems

    •     Pain, tenderness, redness, or swelling where the shot was given (about 1 person in 4)

    •     Fever (mainly in children)

    •     Headache, muscle aches (mainly in adults)

    Moderate or severe problems

    Studies have shown that severe reactions to JE vaccine are very rare.

    Problems that can happen after any vaccine

    •     Brief fainting spells can happen after any medical procedure, including vaccination. Sitting or lying down for about 15 minutes can help prevent fainting, and injuries caused by a fall. Tell your doctor if you feel dizzy, or have vision changes or ringing in the ears

    •     Lasting shoulder pain and reduced range of motion in the arm where the shot was given can happen, very rarely, after a vaccination

    •     Severe allergic reactions from a vaccine are very rare, estimated at less than 1 in a million doses. If one were to occur, it would usually be within a few minutes to a few hours after the vaccination


    What if there is a serious reaction?

    What should I look for?

    Look for anything that concerns you, such as signs of a severe allergic reaction, very high fever, or behavior changes. Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination.

    What should I do?

    If you think it is a severe allergic reaction or other emergency that can't wait, call 120 or get the person to the nearest hospital. Otherwise, call your doctor.

    Where can I get more information?

    •    Jiahui Health

    Contact number: 400-868-3000

    •    Shanghai Municipal Center for Disease Control & Prevention 

    Contact number: 021-62758710

    Website: http://www.scdc.sh.cn


    The US Centers for Disease Control and Prevention. Vaccine Information Statement: Japanese Encephalitis Vaccine01/24/2014

    Click the link for more information on Family Medicine Clinical Service

    Click the link for more information on Pediatrics Clinical Service



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